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Obesity resulting from an increase in the size of fat cells is termed


A) hyperplastic obesity.
B) hypertrophic obesity.
C) idiopenthic leptinemia.
D) anaplastic hypometabolism.

E) A) and B)
F) All of the above

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An important aid in any weight-loss diet program is to


A) decrease water intake.
B) increase physical activity.
C) speed up thyroid activity with metabolic enhancers.
D) develop ketosis by keeping carbohydrate intake as low as possible.

E) B) and D)
F) None of the above

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Which of the following describes a relationship between leptin and energy balance?


A) Fat cell sensitivity to leptin is higher in obese people
B) A deficiency of leptin is characteristic of all obese people
C) Blood levels of leptin usually correlate directly with body fat
D) Major functions of leptin include an increase in hunger and a decrease in metabolic rate

E) A) and B)
F) A) and C)

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Television watching contributes to obesity for all of the following reasons except


A) it promotes inactivity.
B) it promotes between-meal snacking.
C) it replaces time that could be spent eating.
D) it gives high exposure to energy-dense foods featured in the commercial advertisements.

E) All of the above
F) B) and C)

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Which of the following would not be part of a successful program of weight gain in an underweight individual?


A) Eat energy-dense foods
B) Drink energy-dense beverages
C) Eat a large number of small meals
D) Engage in regular physical exercise

E) B) and C)
F) All of the above

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What is a safe rate of weight loss on a long-term basis for most overweight people?


A) 0.5-2 lbs/week
B) 3-4 lbs/week
C) 5% body weight/month
D) 10% body weight/month

E) A) and B)
F) A) and C)

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What is the significance of the uncoupling proteins in adipose tissue?


A) Increased loss of body heat
B) Reduction of fat cell number
C) Lowering of basal metabolism
D) Proliferation of fat cell number

E) A) and B)
F) None of the above

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Among the following, which is the most important strategy for an underweight person who wishes to achieve a healthy body weight?


A) A high-kcalorie diet plus regular exercise
B) A high-kcalorie diet and minimal exercise
C) A high-protein diet plus regular exercise
D) Total elimination of alcohol and exercise

E) A) and C)
F) All of the above

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Compared with non-obese people, obese people have a lower


A) basal metabolic rate.
B) thermic effect of food.
C) physical activity level.
D) metabolic response to exercise.

E) None of the above
F) A) and D)

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Because obesity apparently has many causes, even in an individual, the best approach seems to be


A) fasting.
B) medicines.
C) prevention.
D) genetic counseling.

E) A) and B)
F) C) and D)

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Tom was overweight when he was 13.During puberty he continued to gain weight steadily until at age 23, when he decided to lose weight.Tom successfully lost 50 pounds.Which of the following most likely happened to Tom's fat cells?


A) They shrank in size but did not decrease in number
B) They melted away when he burned all the excess fat
C) They decreased in number but did not decrease in size
D) They changed very little since fat cells shrink only with a weight loss greater than 100 pounds

E) A) and D)
F) B) and C)

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In the quest for achieving desirable body weight, adults have control over all of the following except


A) diet.
B) behavior.
C) physical activity.
D) adipocyte number.

E) A) and C)
F) All of the above

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All of the following are characteristics of the results of weight-loss surgery except


A) hunger is suppressed.
B) deficiencies of vitamins and minerals are common in the long term.
C) dramatic improvements are seen in blood lipids, diabetes, and blood pressure.
D) medical supervision in the postsurgery period is required only for the first 6-9 months.

E) A) and C)
F) B) and C)

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What serves as the body's chief storage site for lipids?


A) Yellow fat
B) Brown adipose tissue
C) White adipose tissue
D) High-density lipoproteins

E) B) and C)
F) A) and B)

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Which of the following is a feature of ghrelin?


A) It is a metabolic antagonist of leptin
B) It stimulates appetite and energy storage
C) The blood level in the fasting state correlates directly with body weight
D) It is released in high amounts from adipocytes during periods of excess energy intake

E) All of the above
F) None of the above

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As a new assistant in a weight-loss research laboratory, you are given a tour of the mouse laboratory.Why is the leptin-deficient mouse much larger than its leptin-sufficient counterpart?


A) Leptin deficiency causes lower levels of ghrelin
B) Leptin deficiency enhances appetite and decreases energy expenditure
C) Leptin deficiency causes psychological depression, which leads to increased food intake
D) Leptin deficiency reduces the desire to do physical activity, resulting in more excess energy available for fat storage

E) B) and C)
F) A) and D)

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The drug sibutramine reduces appetite by affecting


A) ketone production.
B) insulin to glucagon ratio.
C) leptin sensitivity of fat cells.
D) serotonin utilization in the brain.

E) A) and B)
F) B) and C)

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Which of the following is known to cause a reduction in fat cell number in mice?


A) Injection of leptin
B) Supplements of ghrelin
C) Long-term resistance exercise
D) Consumption of high-protein diets

E) B) and D)
F) All of the above

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What is the principal reason that the FDA has banned the sale of products containing ephedrine?


A) The costs are prohibitive
B) The products were found to be ineffective for weight loss
C) The products were implicated in several cases of heart attacks and seizures
D) The products were found to contain contaminants that were believed to be responsible for inducing liver failure

E) None of the above
F) B) and C)

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To help maximize the long-term success of a person's weight-loss program, which of the following personal attitudes should be encouraged in the individual?


A) Strongly believing that weight can be lost
B) Viewing the body realistically as being fat rather than thin
C) Refraining from expressing overconfidence in ability to lose weight
D) Accepting that little or no exercise is a part of the lifestyle of most overweight people

E) B) and D)
F) None of the above

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