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The type of lamellae found in osteons (Haversian systems) is


A) circumferential.
B) concentric.
C) interstitial.
D) appositional.
E) oppositional.

F) A) and B)
G) None of the above

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Which type of bone cells combine hydroxyapatite and collagen to form extracellular bone matrix?


A) osteochondral progenitor cell
B) osteoblasts
C) osteocytes
D) osteoclasts

E) B) and D)
F) All of the above

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What chemical stimulates the spurt of bone growth that occurs at puberty?


A) growth hormone
B) sex hormones
C) parathyroid hormone
D) calcitonin
E) vitamin D

F) A) and C)
G) B) and E)

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What is the membrane that lines the medullary cavity?


A) epiphysis
B) fibers
C) growth plate
D) medullary cavity
E) endosteum

F) C) and D)
G) B) and E)

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How does the muscular system contribute to osteoporosis?


A) inadequate amounts of calcium and vitamin D in the diet
B) lack of exercise reduces muscle stress on bone
C) pain following injury helps prevent further injury
D) blood clotting starts repair process
E) calcitonin is used to treat osteoporosis

F) B) and E)
G) D) and E)

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The growth spurt seen in puberty is triggered by


A) parathyroid hormone.
B) sex hormones.
C) growth hormone.
D) thyroid hormone.
E) calcitonin.

F) A) and B)
G) A) and C)

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Haversian systems or osteons


A) are found in spongy bone tissue.
B) lack concentric lamellae.
C) are the basic units in compact bone tissue.
D) do not contain osteocytes.
E) are avascular.

F) A) and B)
G) B) and E)

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What type of tissue covers the ends of long bones?


A) articular cartilage
B) periosteum
C) elastic cartilage
D) cancellous bone
E) fibrocartilage

F) A) and B)
G) A) and D)

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In which of the following locations in a growing bone would the greatest osteoclast activity be found?


A) epiphysis
B) epiphyseal plate
C) medullary cavity
D) articular cartilage
E) perichondrium

F) A) and E)
G) A) and B)

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Ossification that involves replacing cartilage with bone is


A) intramembranous.
B) endochondral.
C) interstitial.
D) appositional.
E) osteomalacia.

F) None of the above
G) A) and C)

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In which type of bone would trabeculae be present?


A) spongy bone
B) compact bone
C) both spongy and compact

D) All of the above
E) B) and C)

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The primary mineral in bone is


A) sodium.
B) oxygen.
C) calcium.
D) potassium.
E) iron.

F) All of the above
G) A) and E)

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What is the area where marrow is located?


A) periosteum
B) Sharpey fibers
C) growth plate
D) medullary cavity
E) endosteum

F) A) and E)
G) A) and B)

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What chemical causes a decrease in the blood calcium level?


A) growth hormone
B) sex hormones
C) parathyroid hormone
D) calcitonin
E) vitamin D

F) A) and E)
G) C) and E)

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What is the end of a long bone?


A) epiphysis
B) Sharpey's fibers
C) growth plate
D) medullary cavity
E) endosteum

F) A) and D)
G) All of the above

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Which of the following is correctly matched?


A) osteocytes - function in bone remodeling
B) osteoclasts - responsible for reabsorption
C) osteoblasts - break down bone tissue
D) endosteum - lines central canal of the osteon
E) periosteum - lines the medullary cavity

F) None of the above
G) C) and D)

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Osteogenesis imperfecta is


A) bone inflammation that often results from bacterial infection.
B) a disease in adults, especially women, characterized by a reduced amount of bone matrix.
C) a disease in adults characterized by softening of bones resulting from calcium depletion.
D) a disease in children characterized by soft, bowed, and swollen bones.
E) a group of genetic disorders producing very brittle bones that are easily fractured; occurs because of insufficient collagen development.

F) A) and E)
G) A) and D)

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Which of the following occurs in the formation of mineralized bone matrix?


A) Hydrogen ions form an acid environment in bone matrix.
B) Osteoblasts form collagen and proteoglycans.
C) The protein components of bone matrix are digested.
D) Ca2+ is actively transported from bone matrix to the blood.
E) Blood calcium is elevated.

F) A) and E)
G) None of the above

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The longitudinal growth of long bones ceases when


A) chondroblasts take over mitosis of osteoblasts.
B) the epiphyseal plate is completely replaced with bone tissue.
C) the epiphysis becomes separated from the diaphysis.
D) the bone marrow forms.
E) the periosteum is completed.

F) B) and C)
G) A) and E)

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How does the reproductive system contribute to osteoporosis?


A) Lack of exposure to sunlight reduces vitamin D production and decreases calcium absorption.
B) Immune cells resist infections and release chemicals that promote tissue repair.
C) Excessive smoking lowers estrogen levels, which increases bone loss.
D) Calcium ions released from the bones are excreted.
E) Decreased estrogen levels following menopause contribute to the disease.

F) B) and C)
G) B) and E)

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